PLCglow (WH-15) - click on links to open reference:

Small molecule inhibitors of phospholipase C from a novel high-throughput screen.

Huang W, Barrett M, Hajicek N, Hicks S, Harden TK, Sondek J, Zhang Q. J Biol Chem. 2013 Feb 22;288(8):5840-8. doi: 10.1074/jbc.M112.422501. Epub 2013 Jan 7.

 

A fluorogenic, small molecule reporter for mammalian phospholipase C isozymes.

Huang W, Hicks SN, Sondek J, Zhang Q. ACS Chem Biol. 2011 Mar 18;6(3):223-8. doi: 10.1021/cb100308n. Epub 2011 Jan 10.
 

Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1). [Primary Screening]

Source: The Scripps Research Institute Molecular Screening Center
Protein Target: Phospholipase C, gamma 1 [Homo sapiens]
 

Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3). [Primary Screening]

Source: The Scripps Research Institute Molecular Screening Center
Protein Target: Phospholipase C, beta 3 (phosphatidylinositol-specific) [Homo sapiens]
 

GTPase exchange assays:

Selected literature references coming soon.